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Drugs: Signed, Sealed, Distributed Exploring the importance of Volume of Distribution
Kinase-linked receptors What are KLRs? A kinase-linked receptor (KLR) is a transmembrane receptor, which uses second messenger signaling that triggers a cascade of cellular events. Ligands bind to the receptor-binding site at the extracellular domain, which causes phosphorylation of amino acids, mainly tyrosine, within the intracellular domain. Phosphorylation initiates...
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During an average lifetime, it is very common to come across ‘DRUGS’, ‘pH’, ‘pKa’ and Pharmacology…. What do they REALLY mean? Of course….why would it matter to us? Well… This is one of the reasons WHY!!! We have all gone through some sort of challenge, test or major examination….so imagine having to...